"category_id"	"n_genesets_mapped"	"n_genesets_evaluable"	"n_genesets_unavailable"	"n_genesets_significant"	"n_pos_genesets"	"n_neg_genesets"	"n_zero_genesets"	"mean_NES"	"median_NES"	"p25_NES"	"p75_NES"	"positive_pct"	"negative_pct"	"zero_pct"	"same_direction_pct"	"mean_NES_direction"	"gsea_padj_cutoff"	"quantile_type"	"category_display_name"	"macrogroup_name"	"category_color"	"source_row_order"	"side"	"display_mean_NES"	"endpoint_state"	"display_color"
"DEVELOPMENT_MORPHOGENESIS"	"              1010"	"               716"	"               294"	"               236"	"               131"	"               105"	"                 0"	"0.15230420874514722"	"1.2642083771833703"	"-1.4065029769629604"	" 1.434656312318616"	"55.508474576271183"	"44.491525423728817"	"                 0"	"55.508474576271183"	"Positive NES"	"              0.25"	"                 7"	"Development and morphogenesis"	"Developmental and neural programs"	"#E88BA1"	"                 1"	"single"	"0.15230420874514722"	"significant_support"	"#b2182b"
"NEUROGENESIS_SYNAPSE"	"               791"	"               579"	"               212"	"               144"	"                43"	"               101"	"                 0"	"-0.57528800956359261"	"-1.3299091494426394"	"-1.4972556924862586"	"1.3007440396102776"	"29.861111111111111"	"70.138888888888886"	"                 0"	"70.138888888888886"	"Negative NES"	"              0.25"	"                 7"	"Neurogenesis and synapse"	"Developmental and neural programs"	"#B9576E"	"                 2"	"single"	"-0.57528800956359261"	"significant_support"	"#2166ac"
"DNA_DAMAGE_REPAIR_CHECKPOINTS"	"               295"	"               236"	"                59"	"               146"	"                 5"	"               141"	"                 0"	"-1.6152394115436937"	"-1.674720533921066"	"-1.8794803172786601"	"-1.4862901222454183"	"3.4246575342465753"	"96.575342465753423"	"                 0"	"96.575342465753423"	"Negative NES"	"              0.25"	"                 7"	"DNA damage, repair and checkpoints"	"Genome and gene expression"	"#D99A66"	"                 3"	"single"	"-1.6152394115436937"	"significant_support"	"#2166ac"
"RNA_PROCESSING_SPLICING_RNP"	"               263"	"               185"	"                78"	"               125"	"                 7"	"               118"	"                 0"	"-1.5356243415147033"	"-1.7084674512646361"	"-1.8600563790043736"	"-1.4638553944952211"	"5.5999999999999996"	"94.400000000000006"	"                 0"	"94.400000000000006"	"Negative NES"	"              0.25"	"                 7"	"RNA processing and RNP biology"	"Genome and gene expression"	"#D18649"	"                 4"	"single"	"-1.5356243415147033"	"significant_support"	"#2166ac"
"TRANSCRIPTION_CHROMATIN_EPIGENETICS"	"               416"	"               326"	"                90"	"               146"	"                39"	"               107"	"                 0"	"-0.81860026495709348"	"-1.5003724124229807"	"-1.7769565025738676"	" 1.259818637732472"	"26.712328767123289"	"73.287671232876718"	"                 0"	"73.287671232876718"	"Negative NES"	"              0.25"	"                 7"	"Transcription, chromatin and epigenetics"	"Genome and gene expression"	"#C17537"	"                 5"	"single"	"-0.81860026495709348"	"significant_support"	"#2166ac"
"TRANSLATION_RIBOSOME"	"               116"	"                85"	"                31"	"                60"	"                 0"	"                60"	"                 0"	"-1.862194918899529"	"-1.8251907141217019"	"-2.0649779708702027"	"-1.5034768708602404"	"                 0"	"               100"	"                 0"	"               100"	"Negative NES"	"              0.25"	"                 7"	"Translation and ribosome"	"Genome and gene expression"	"#A96730"	"                 6"	"single"	"-1.862194918899529"	"significant_support"	"#2166ac"
"IMMUNE_ADAPTIVE_ANTIGEN_MHC"	"               328"	"               254"	"                74"	"               238"	"               237"	"                 1"	"                 0"	"2.1275638296982473"	"2.1596138189056679"	"1.8600207085683871"	"2.4931381367320133"	"99.579831932773104"	"0.42016806722689076"	"                 0"	"99.579831932773104"	"Positive NES"	"              0.25"	"                 7"	"Adaptive immunity and antigen presentation"	"Immune and inflammatory biology"	"#BDA838"	"                 7"	"single"	"2.1275638296982473"	"significant_support"	"#b2182b"
"IMMUNE_CYTOKINE_INFLAMMATORY"	"               535"	"               428"	"               107"	"               376"	"               372"	"                 4"	"                 0"	"1.8481578004349328"	"1.8764011088568113"	"1.6264031166781348"	"2.1173499703543341"	"98.936170212765958"	"1.0638297872340425"	"                 0"	"98.936170212765958"	"Positive NES"	"              0.25"	"                 7"	"Cytokine and inflammatory signaling"	"Immune and inflammatory biology"	"#B09812"	"                 8"	"single"	"1.8481578004349328"	"significant_support"	"#b2182b"
"IMMUNE_CORE"	"               185"	"               134"	"                51"	"               117"	"               115"	"                 2"	"                 0"	"2.0053056409441892"	"2.0111139136972662"	"1.7263580131764504"	"2.3609550689466086"	"98.290598290598297"	"1.7094017094017093"	"                 0"	"98.290598290598297"	"Positive NES"	"              0.25"	"                 7"	"Immune core"	"Immune and inflammatory biology"	"#9F8700"	"                 9"	"single"	"2.0053056409441892"	"significant_support"	"#b2182b"
"IMMUNE_INNATE_COMPLEMENT_PRR"	"               308"	"               223"	"                85"	"               186"	"               183"	"                 3"	"                 0"	"1.8434065742960719"	"1.8673404373744129"	"1.6421071361557813"	"2.1141770590700184"	"98.387096774193552"	"1.6129032258064515"	"                 0"	"98.387096774193552"	"Positive NES"	"              0.25"	"                 7"	"Innate immunity, complement and PRR"	"Immune and inflammatory biology"	"#8B7600"	"                10"	"single"	"1.8434065742960719"	"significant_support"	"#b2182b"
"METABOLISM_AA_ONECARBON"	"               251"	"               156"	"                95"	"                92"	"                87"	"                 5"	"                 0"	"1.5769681959036241"	"1.6900771590817598"	"1.5289016247384857"	"1.9601090503733727"	"94.565217391304344"	"5.4347826086956523"	"                 0"	"94.565217391304344"	"Positive NES"	"              0.25"	"                 7"	"Amino acid and one-carbon metabolism"	"Metabolism and bioenergetics"	"#8FB438"	"                11"	"single"	"1.5769681959036241"	"significant_support"	"#b2182b"
"METABOLISM_CARBOHYDRATE_GLYCOLYSIS"	"               172"	"               112"	"                60"	"                39"	"                37"	"                 2"	"                 0"	"1.3615204505956426"	"1.4646370885162765"	"1.3552459842740952"	"1.5805933176280282"	"94.871794871794876"	"5.1282051282051286"	"                 0"	"94.871794871794876"	"Positive NES"	"              0.25"	"                 7"	"Carbohydrate metabolism and glycolysis"	"Metabolism and bioenergetics"	"#85AE28"	"                12"	"single"	"1.3615204505956426"	"significant_support"	"#b2182b"
"DETOX_XENOBIOTIC_METABOLISM"	"               126"	"                87"	"                39"	"                64"	"                64"	"                 0"	"                 0"	"1.7569051085376295"	"1.7514929155671073"	"1.5814050084344098"	"1.9104202487061117"	"               100"	"                 0"	"                 0"	"               100"	"Positive NES"	"              0.25"	"                 7"	"Detoxification and xenobiotic metabolism"	"Metabolism and bioenergetics"	"#7CA818"	"                13"	"single"	"1.7569051085376295"	"significant_support"	"#b2182b"
"METABOLISM_CORE"	"                51"	"                41"	"                10"	"                28"	"                22"	"                 6"	"                 0"	"0.95188996338489384"	"1.5160080430961633"	"1.2753789933304236"	"1.6988923551663846"	"78.571428571428569"	"21.428571428571427"	"                 0"	"78.571428571428569"	"Positive NES"	"              0.25"	"                 7"	"General metabolism"	"Metabolism and bioenergetics"	"#73A208"	"                14"	"single"	"0.95188996338489384"	"significant_support"	"#b2182b"
"METABOLISM_LIPID_FA"	"               637"	"               460"	"               177"	"               253"	"               244"	"                 9"	"                 0"	"1.6415117379039765"	"1.7420503105114733"	"1.5185731304856906"	"1.9231579806022563"	"96.442687747035578"	"3.5573122529644268"	"                 0"	"96.442687747035578"	"Positive NES"	"              0.25"	"                 7"	"Lipid and fatty acid metabolism"	"Metabolism and bioenergetics"	"#6C9A00"	"                15"	"single"	"1.6415117379039765"	"significant_support"	"#b2182b"
"MITOCHONDRIA_OXPHOS_ETC"	"               143"	"               110"	"                33"	"                67"	"                 4"	"                63"	"                 0"	"-1.6950180744366596"	"-1.9083942911774716"	"-2.1443555058748842"	"-1.5249747117026438"	"5.9701492537313436"	" 94.02985074626865"	"                 0"	" 94.02985074626865"	"Negative NES"	"              0.25"	"                 7"	"Mitochondria, OXPHOS and ETC"	"Metabolism and bioenergetics"	"#669200"	"                16"	"single"	"-1.6950180744366596"	"significant_support"	"#2166ac"
"METABOLISM_NUCLEOTIDE"	"               175"	"               115"	"                60"	"                61"	"                32"	"                29"	"                 0"	"0.026303706523623658"	"1.2449915121604853"	"-1.5471641959258415"	" 1.444380481698065"	"52.459016393442624"	"47.540983606557376"	"                 0"	"52.459016393442624"	"Positive NES"	"              0.25"	"                 7"	"Nucleotide metabolism"	"Metabolism and bioenergetics"	"#608A00"	"                17"	"single"	"0.026303706523623658"	"significant_support"	"#b2182b"
"PEROXISOME_FAO"	"                21"	"                12"	"                 9"	"                 5"	"                 5"	"                 0"	"                 0"	" 2.055325886006178"	"2.0991512690202052"	"2.0702539449434072"	"   2.1128774987985"	"               100"	"                 0"	"                 0"	"               100"	"Positive NES"	"              0.25"	"                 7"	"Peroxisome and fatty acid oxidation"	"Metabolism and bioenergetics"	"#5B8200"	"                18"	"single"	" 2.055325886006178"	"significant_support"	"#b2182b"
"ECM_MATRIX_REMODELING"	"               183"	"               142"	"                41"	"                65"	"                62"	"                 3"	"                 0"	"1.4393534352173165"	"1.5580059819051411"	"1.3875339127895996"	"1.7187443614697906"	"95.384615384615387"	" 4.615384615384615"	"                 0"	"95.384615384615387"	"Positive NES"	"              0.25"	"                 7"	"ECM and matrix remodeling"	"Microenvironment, vascular and ECM"	"#38BD7E"	"                19"	"single"	"1.4393534352173165"	"significant_support"	"#b2182b"
"VASCULAR_LYMPHATIC"	"               151"	"               107"	"                44"	"                65"	"                65"	"                 0"	"                 0"	"1.6691491760671271"	"1.6310379023324395"	"1.5135979550861891"	" 1.824748550056297"	"               100"	"                 0"	"                 0"	"               100"	"Positive NES"	"              0.25"	"                 7"	"Vascular, angiogenic and lymphatic biology"	"Microenvironment, vascular and ECM"	"#008B4A"	"                20"	"single"	"1.6691491760671271"	"significant_support"	"#b2182b"
"CELL_CYCLE_PROLIFERATION"	"               555"	"               417"	"               138"	"               259"	"                35"	"               224"	"                 0"	"-1.3009424500396374"	"-1.6568962699144434"	"-1.9214783422314148"	"-1.390374913088142"	"13.513513513513514"	"86.486486486486484"	"                 0"	"86.486486486486484"	"Negative NES"	"              0.25"	"                 7"	"Cell cycle and proliferation"	"Proliferation and cell cycle"	"#00AD9A"	"                21"	"single"	"-1.3009424500396374"	"significant_support"	"#2166ac"
"SIGNALING_CORE"	"               714"	"               555"	"               159"	"               219"	"               202"	"                17"	"                 0"	"1.3777939891129125"	" 1.570339560108702"	"1.3773716604304369"	" 1.734522397203961"	"92.237442922374427"	" 7.762557077625571"	"                 0"	"92.237442922374427"	"Positive NES"	"              0.25"	"                 7"	"Core cell signaling"	"Signaling and cell communication"	"#38BAD6"	"                22"	"single"	"1.3777939891129125"	"significant_support"	"#b2182b"
"ENDOCRINE_HORMONAL"	"               497"	"               367"	"               130"	"               142"	"               135"	"                 7"	"                 0"	"1.4221215326994947"	"1.5004853578963926"	"1.3795887384411718"	"1.7087957069936088"	"95.070422535211264"	" 4.929577464788732"	"                 0"	"95.070422535211264"	"Positive NES"	"              0.25"	"                 7"	"Endocrine and hormonal pathways"	"Signaling and cell communication"	"#1CB0D0"	"                23"	"single"	"1.4221215326994947"	"significant_support"	"#b2182b"
"GROWTH_FACTOR_RTK"	"               412"	"               328"	"                84"	"                68"	"                56"	"                12"	"                 0"	"1.0171721553654651"	"1.4619989375213649"	"1.3304014592252871"	"1.6276841601799801"	"82.352941176470594"	"17.647058823529413"	"                 0"	"82.352941176470594"	"Positive NES"	"              0.25"	"                 7"	"Growth factor and RTK pathways"	"Signaling and cell communication"	"#00A6CA"	"                24"	"single"	"1.0171721553654651"	"significant_support"	"#b2182b"
"TGFB_SMAD"	"               129"	"               101"	"                28"	"                28"	"                26"	"                 2"	"                 0"	"1.2452204482992384"	"1.3660473455879838"	"1.3372055837366195"	"1.5491895213697635"	"92.857142857142861"	"7.1428571428571432"	"                 0"	"92.857142857142861"	"Positive NES"	"              0.25"	"                 7"	"TGF-beta and SMAD signaling"	"Signaling and cell communication"	"#0097B8"	"                25"	"single"	"1.2452204482992384"	"significant_support"	"#b2182b"
"WNT_NOTCH_HEDGEHOG_HIPPO"	"               263"	"               210"	"                53"	"                54"	"                16"	"                38"	"                 0"	"-0.60571683699624812"	"-1.3762951430023578"	"-1.5019562616797897"	"1.3189939321501083"	" 29.62962962962963"	"70.370370370370367"	"                 0"	"70.370370370370367"	"Negative NES"	"              0.25"	"                 7"	"Wnt, Notch, Hedgehog and Hippo"	"Signaling and cell communication"	"#0088A6"	"                26"	"single"	"-0.60571683699624812"	"significant_support"	"#2166ac"
"APOPTOSIS_CELL_DEATH"	"               321"	"               231"	"                90"	"                90"	"                77"	"                13"	"                 0"	"1.2143693730945113"	"1.5672983824610016"	"1.4262329029191119"	"1.7686973424258694"	"85.555555555555557"	"14.444444444444445"	"                 0"	"85.555555555555557"	"Positive NES"	"              0.25"	"                 7"	"Apoptosis and regulated cell death"	"Stress, proteostasis and cell death"	"#7EA9EA"	"                27"	"single"	"1.2143693730945113"	"significant_support"	"#b2182b"
"AUTOPHAGY_LYSOSOME"	"               154"	"               110"	"                44"	"                26"	"                17"	"                 9"	"                 0"	"0.60683525846540609"	"1.3542127688224141"	"-1.2911592475372138"	"1.5808421130143984"	"65.384615384615387"	"34.615384615384613"	"                 0"	"65.384615384615387"	"Positive NES"	"              0.25"	"                 7"	"Autophagy, lysosome and phagosome maturation"	"Stress, proteostasis and cell death"	"#71A1E8"	"                28"	"single"	"0.60683525846540609"	"significant_support"	"#b2182b"
"ER_STRESS_UPR"	"                48"	"                36"	"                12"	"                 3"	"                 3"	"                 0"	"                 0"	"1.4390886776277143"	"1.4375676108220825"	"1.3697825376279473"	"1.5076342842246655"	"               100"	"                 0"	"                 0"	"               100"	"Positive NES"	"              0.25"	"                 7"	"ER stress and unfolded protein response"	"Stress, proteostasis and cell death"	"#6599E6"	"                29"	"single"	"1.4390886776277143"	"significant_support"	"#b2182b"
"HEAT_SHOCK_STRESS_RESPONSE"	"                17"	"                14"	"                 3"	"                 8"	"                 1"	"                 7"	"                 0"	"-1.2318204652147182"	"-1.6451919119530825"	"-1.7550127331287577"	"-1.2809462032878174"	"              12.5"	"              87.5"	"                 0"	"              87.5"	"Negative NES"	"              0.25"	"                 7"	"Heat shock and acute stress response"	"Stress, proteostasis and cell death"	"#5991E4"	"                30"	"single"	"-1.2318204652147182"	"significant_support"	"#2166ac"
"HYPOXIA_HIF"	"                31"	"                21"	"                10"	"                 7"	"                 7"	"                 0"	"                 0"	"1.5158510219577288"	" 1.499024944889217"	"1.4894284024797151"	"1.5418266217419232"	"               100"	"                 0"	"                 0"	"               100"	"Positive NES"	"              0.25"	"                 7"	"Hypoxia and HIF programs"	"Stress, proteostasis and cell death"	"#5388D6"	"                31"	"single"	"1.5158510219577288"	"significant_support"	"#b2182b"
"OXIDATIVE_STRESS_REDOX_ROS"	"               116"	"                87"	"                29"	"                40"	"                36"	"                 4"	"                 0"	"1.2438922196018185"	"1.4454291402468522"	"1.3288228492634939"	"1.6347485182991697"	"                90"	"                10"	"                 0"	"                90"	"Positive NES"	"              0.25"	"                 7"	"Oxidative stress, redox and ROS"	"Stress, proteostasis and cell death"	"#4E7FC8"	"                32"	"single"	"1.2438922196018185"	"significant_support"	"#b2182b"
"PROTEOSTASIS_UBIQUITIN_PROTEASOME"	"               214"	"               162"	"                52"	"                72"	"                 8"	"                64"	"                 0"	"-1.1748482444153925"	"-1.5069459966870031"	"-1.6175979859575198"	"-1.3095308191984283"	"11.111111111111111"	"88.888888888888886"	"                 0"	"88.888888888888886"	"Negative NES"	"              0.25"	"                 7"	"Proteostasis, ubiquitin and proteasome"	"Stress, proteostasis and cell death"	"#4977BB"	"                33"	"single"	"-1.1748482444153925"	"significant_support"	"#2166ac"
"ADHESION_JUNCTION_POLARITY"	"               260"	"               205"	"                55"	"               103"	"                82"	"                21"	"                 0"	"1.0552006892477919"	"1.6022810094937505"	"1.3343057582474998"	"1.8284914593589288"	"79.611650485436897"	"20.388349514563107"	"                 0"	"79.611650485436897"	"Positive NES"	"              0.25"	"                 7"	"Adhesion, junctions and polarity"	"Structure, motility and plasticity"	"#C693E7"	"                34"	"single"	"1.0552006892477919"	"significant_support"	"#b2182b"
"CYTOSKELETON_CONTRACTILITY"	"               419"	"               319"	"               100"	"               162"	"                85"	"                77"	"                 0"	"0.01318414220941549"	"1.2196059889333686"	"-1.534000846041379"	"1.4541274093823278"	"52.469135802469133"	"47.530864197530867"	"                 0"	"52.469135802469133"	"Positive NES"	"              0.25"	"                 7"	"Cytoskeleton and contractility"	"Structure, motility and plasticity"	"#BB7FE2"	"                35"	"single"	"0.01318414220941549"	"significant_support"	"#b2182b"
"EMT_PLASTICITY"	"                34"	"                21"	"                13"	"                 4"	"                 4"	"                 0"	"                 0"	"1.5120063970222286"	"1.5053615259475981"	"1.4126040623762643"	"1.6047638605935621"	"               100"	"                 0"	"                 0"	"               100"	"Positive NES"	"              0.25"	"                 7"	"EMT and cell-state plasticity"	"Structure, motility and plasticity"	"#AB6DD2"	"                36"	"single"	"1.5120063970222286"	"significant_support"	"#b2182b"
"MIGRATION_INVASION"	"               215"	"               150"	"                65"	"                92"	"                86"	"                 6"	"                 0"	"1.6296587479188192"	"1.8192357351445425"	"1.5361408908913967"	"2.0566030520182021"	"93.478260869565219"	"6.5217391304347823"	"                 0"	"93.478260869565219"	"Positive NES"	"              0.25"	"                 7"	"Migration, invasion and motility programs"	"Structure, motility and plasticity"	"#9560B8"	"                37"	"single"	"1.6296587479188192"	"significant_support"	"#b2182b"
"ION_TRANSPORT_HOMEOSTASIS"	"               382"	"               272"	"               110"	"                83"	"                73"	"                10"	"                 0"	"1.2251471874400395"	"1.5154814349571519"	"1.3810855678090319"	"1.6710680507609985"	"87.951807228915669"	"12.048192771084338"	"                 0"	"87.951807228915669"	"Positive NES"	"              0.25"	"                 7"	"Ion transport and homeostasis"	"Transport, trafficking and homeostasis"	"#E486CC"	"                38"	"single"	"1.2251471874400395"	"significant_support"	"#b2182b"
"TRANSPORT_LOCALIZATION"	"               418"	"               293"	"               125"	"               139"	"                82"	"                57"	"                 0"	"0.24906491712723128"	"1.3617556611970729"	"-1.4568291037022716"	"1.4938978201228501"	"58.992805755395686"	"41.007194244604314"	"                 0"	"58.992805755395686"	"Positive NES"	"              0.25"	"                 7"	"Transport and localization"	"Transport, trafficking and homeostasis"	"#DD64BE"	"                39"	"single"	"0.24906491712723128"	"significant_support"	"#b2182b"
"VESICLE_SECRETORY_TRAFFICKING"	"               373"	"               282"	"                91"	"                87"	"                43"	"                44"	"                 0"	"-0.014222869324192627"	"-1.1486148033420711"	"-1.5279989172760167"	"1.4770755055154308"	"49.425287356321839"	"50.574712643678161"	"                 0"	"50.574712643678161"	"Negative NES"	"              0.25"	"                 7"	"Vesicle, endocytosis, exocytosis and secretion"	"Transport, trafficking and homeostasis"	"#B5529C"	"                40"	"single"	"-0.014222869324192627"	"significant_support"	"#2166ac"